ELi5: Why does certain alcohol effect people differently?

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I can drink whiskey all night and have a lovely time in good spirits and no hangover the next day.
But I’ve seen otherwise nice people turn into demons on whiskey and people have told me it gives them severe hangovers.

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Anonymous 0 Comments

Whiskey (especially Bourbon) has a lot of varying proofs than say tequila or vodka which are gonna hover around 80. Soon as you start sipping whiskies, proof (measurement or alcohol concentration) goes up. Bourbon starts at 90 and can easily get into the 120s. The latter drinks are also accompanied by more mixers (sugar) than whiskey drinks. Sugar affects the body’s ability to metabolize exclusively alcohol.

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