1st, any completely healthy blood wouldn’t be your blood so you would have to deal with rejection, which likely would be even worse than the symptoms of the disease you already have.
And 2nd, even if you find a perfectly compatible donor so that is not an issue you are still talking liters of blood. This would be very time consuming and expensive.
And 3rd, you are still constantly producing new blood so you still have a lot of blood with the underlying issue even a day after you do this procedure.
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