The short version: From the 1930s to the 1050s, a lot of DDT was sprayed, a lot of other insecticides, and a lot of swampland was cleared out.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8168761/
Here’s a link from the NIH that tells you the same thing, but with big words and more detail.
There are still several hundred cases of malaria a year in Italy but they’re all imported.
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