We don’t know if it can. we don’t even know if there is permanent damage from it. The cases where someone did stay up very long, damage reversed after they slept and their routine went back to normal.
We have done experiment on rats where they were kept up and they ended up dying. But we don’t know if that was because they were not allowed to sleep or because they were constantly woken up from their sleep and the stress of that killed them.
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