Every particle in the universe came into existence as one half of a pair of particles: a particle, and its anti-particle.
One of the great mysteries astrophysics is trying to resolve is what happened to all the anti-particles for the matter in the universe we can observe now.
Artificial anti-particles are created in a vacuum in particle accelerators and are confined by magnetic fields to keep them separate from matter.
It’s really hard to do. Most anti-particles created this way exist for small fractions of a second before being annihilated.
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