As the title states, how can people ingest large amounts of sugar from sources and still not get diabetes? Does When you ingest that sugar matter? Like, 39g in the morning, 39g at night (39g being a regular can of coke)?
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Well a lot of them do eventually. They even had to change the name from “adult onset diabetes” to “Type 2 diabetes” because so many young-ish people were showing signs due to obesity and terrible diets.
If that’s all you’re doing and your diet is otherwise fine, a healthier pancreas can power through it. If the rest of your diet is similarly poor, you are highly likely to develop diabetes eventually.
The body is pretty resilient in how it can deal with sudden influxes of nutrients. It had to be – it was literally “feast or famine” up until about 150 years ago or so. We needed to ingest tons of calories when they were available so we’d have them stored for when they were not. Our bodies adapted to deal with this.
Diabetes – in this case Type 2 or adult-onset diabetes – is the result of chronic overindulgence. The body simply can’t keep up with _always_ having too much, so systems start failing. A single can of Coke isn’t going to cause that, but multiple cans every day for _years_ will.
Well a lot of them do eventually. They even had to change the name from “adult onset diabetes” to “Type 2 diabetes” because so many young-ish people were showing signs due to obesity and terrible diets.
If that’s all you’re doing and your diet is otherwise fine, a healthier pancreas can power through it. If the rest of your diet is similarly poor, you are highly likely to develop diabetes eventually.
Well a lot of them do eventually. They even had to change the name from “adult onset diabetes” to “Type 2 diabetes” because so many young-ish people were showing signs due to obesity and terrible diets.
If that’s all you’re doing and your diet is otherwise fine, a healthier pancreas can power through it. If the rest of your diet is similarly poor, you are highly likely to develop diabetes eventually.
Sugar doesn’t cause diabetes. Insulin resistance leads to diabetes. Usually that is caused by fat in the blood blocking cells insulin receptors. This leads to overwork of the pancreas and eventual failure.
The body is pretty resilient in how it can deal with sudden influxes of nutrients. It had to be – it was literally “feast or famine” up until about 150 years ago or so. We needed to ingest tons of calories when they were available so we’d have them stored for when they were not. Our bodies adapted to deal with this.
Diabetes – in this case Type 2 or adult-onset diabetes – is the result of chronic overindulgence. The body simply can’t keep up with _always_ having too much, so systems start failing. A single can of Coke isn’t going to cause that, but multiple cans every day for _years_ will.
The body is pretty resilient in how it can deal with sudden influxes of nutrients. It had to be – it was literally “feast or famine” up until about 150 years ago or so. We needed to ingest tons of calories when they were available so we’d have them stored for when they were not. Our bodies adapted to deal with this.
Diabetes – in this case Type 2 or adult-onset diabetes – is the result of chronic overindulgence. The body simply can’t keep up with _always_ having too much, so systems start failing. A single can of Coke isn’t going to cause that, but multiple cans every day for _years_ will.
Sugar doesn’t cause diabetes. Insulin resistance leads to diabetes. Usually that is caused by fat in the blood blocking cells insulin receptors. This leads to overwork of the pancreas and eventual failure.
Sugar doesn’t cause diabetes. Insulin resistance leads to diabetes. Usually that is caused by fat in the blood blocking cells insulin receptors. This leads to overwork of the pancreas and eventual failure.
Diabetes is just the clinical diagnosis of insulin resistance.
Insulin resistance can be extreme where the body loses ability to pull glucose out of the blood, or it can be very mild where the basal insulin load your body must produce to regulate glucose is higher than it should be.
There’s a lot of good research out there trying to demonstrate that relying solely on blood sugar to diagnose metabolic diabetes is problematic. For example chronically elevated blood pressure is frequently caused by insulin resistance since the kidney re-uptake, or retention of sodium is largely regulated by insulin load. If you’re mildly resistant to insulin you could have perfectly normal blood sugar, but elevated blood pressure.
Insulin resistance is biologically appropriate. When the fall glut of fruit crops up it makes sense for the body to become insulin resistant. More systemic insulin slows down the metabolism, promotes fat gain, and restricts catabolism. Exactly the kinds of things you want for putting on weight before winter. It also blocks leptin signaling on the vagus nerve stimulating appetite. The problem is we never actually go through the famine of winter now.
You can end up with supposed paradoxes in individuals. Being highly active can be protective because that activity helps keep fat from accumulating in the muscles keeping them highly sensitive to insulin allowing them to be a big sink for that glucose. Additionally eating patterns can greatly influence insulin sensitivity. Eating 200g of sugar throughout the day is completely different than eating 200g in one sitting. In one sitting you have one insulin spike, and the rest of the day you have low insulin which promotes catabolism and moving fat away from the organs. If you graze all day the catabolic state is never really achieved.
That’s how you can end up with people who weigh 300lbs but paradoxically have hardly any symptoms associated with metabolic disease. They have no visceral or organ fat. Then you have perfectly normal weight individuals with high blood pressure, diabetes, and a littany of health complaints, but they have high amounts of visceral fat and intramuscular fat.
Get a fasting insulin test. Aboriginal hunter-gatherer populations have fasting insulin around 3.2-3.5. If i remember correctly The women’s health initiative study found a doubling of all cause mortality within 5 years with a fasting insulin of 8.0 vs 7.0. If you get a fasting insulin test it will say you are “normal” if you are under 15…. that normality is based on blood sugar outcome. Not health outcomes. If you’re over 5.0 you are insulin resistant.
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