It seems dreadfully counterintuitive that bites from a tiny creature such as a recluse or black widow spider can have disastrous, even lethal consequences for far larger creatures, like humans. How is this possible, given the seemingly insignificant volumes of venom in question?
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There is a very common biochemical occurrence called a cascade. This means that one small trigger, such as a hormone, can cause a massive amount of reaction in other parts of the body. Your body uses these cascades all over the body to get things done and certain things like venom can stop these processes from happening or make new cascades happen themselves.
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