Well 90+% of our evolution was in small hunter gatherer groups.
It wasnt until about 10k years ago did we figure out agriculture which allowed our species to stay in a single place and refine farming practices.
Then we figured out how to use oil and fossil fuels as energy a couple centuries ago which exploded our global population to the billions. We then figured out how to refine foods and sugars. This is vastly outside our evolutionary roots.
Having access to readily refined foods has a consequence of breeding types of bacteria that feed on such highly processed foods. Think of a piece of fruit that has sugar, but also fiber, and other micronutrients that has a balance forged by evolution. Now we have sugar that isolated and causes novel consequences like diabetes, and cavities.
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