How did remote places in Asia and Africa not succumb to the same wave of disease and death that the Native Americans did?

Question

I’m not saying they weren’t affected at all, but something like 90% of Native Americans were wiped out while places like Japan and deep parts of the African interior didn’t suffer nearly as hard, even though they previously had basically no contact with Europe.

In: 1583

Answer 1

Japan might not have had contact with Europe, but they did have contact with China. China, in turn, had contact with India, which had contact with Persia, which had contact with Europe. All of Eurasia is connected, so plagues were never unique to one part of this land. The bubonic plague came from Mongolia, and cholera came from India. Japan had experienced all the same plagues as Europe, the Americas hadn’t.