Experiments. In one, electrical probes on the frontal cortex of dogs showed that they could produce changes in the amount of alertness and aggression. Studies of brain lesions in humans showed that damage to particular parts of the brain would lead to particular patterns of physical and psychological deficits.
Phineas Gage was a railroad worker who suffered a brain injury when a metal rod went through the front part of his brain. After the accident, he changed from a smart, kind guy to one who was impulsive and rude.
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