Once enamel is gone, it’s gone forever.
What most of these toothpastes do is leave a coating/film/layer on your teeth. How long it lasts is really up for debate, most say the coating lasts 8 hours. You need to follow the instructions so brushing for two minutes and giving each tooth attention and eat nothing for 30mins. Avoid acidic foods, drink with a straw, brush after every meal, floss, etc.
These toothpastes remineralize your existing enamel to make it more resilient against acids, sugars, and bacteria.
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