Moreover, how do they know they are needed, without the guidance of a nucleus?
In: Biology
Platlettes are fragments of a progenitor cell called a megakaryocyte usually found in the bone marrow.
https://en.m.wikipedia.org/wiki/Megakaryocyte
They are always present in your bloodstream. Once the clotting Cascade is activated by any of several mechanisms, they are activated which causes them to clump together and are then trapped by fibrin strands to form the solid part of the clot.
I am a NYS liscensed medical technologist working in a large teaching hospital in the hematology / coagulation lab
Edit: typo
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