I’m still pretty confused about this one, if SNRIs raise norepinephrine, which raises the fight or flight response, then how is that supposed to make anxiety improve?
Wasn’t sure whether to flair this as biology or chemistry
In: 4
Norepinephrine does act in the peripheral nervous system and participates in sympathetic nervous system activation (fight or flight response). However, it also acts in the central nervous system as a neurotransmitter involved in a complex interplay between serotonin and dopamine as well. The exact mechanism is not well described IIRC but the overall effect is one of mood stabilization.
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