The main active ingredient in sourdough starter is yeast (and bacteria). When provided with enough carbohydrates (such as flour) and water it will multiply producing carbon dioxide gas and various other processes that happens when dough rises. So the sourdough starter is essentially alive and needs regular feeding and be kept in a suitable environment. You can kill your starter or at least weaken it if you mishandle it. You can also get it infected which changes its properties and therefore the taste and texture of the bread.
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