SSRIs work by increasing the amount of serotonin in your brain. But they can also have side effects like constipation (the internet says SSRIs block acetylcholine?), and you can’t take NSAIDs too because of a risk of stomach bleeding. How do SSRIs do those things if they are focused on serotonin? Does acetylcholine use the same receptors as serotonin? I’m also interested in how they cause other side effects.
In: Biology
Your gut has a secondary nervous system that controls the movement of food. The neurons of that system work in more or less the same way as the ones in your brain do, so things that change how neurotransmitters like serotonin work generally affect both (although the goal in drug development is usually to find substances that focus specifically on what you’re trying to change).
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