How does a psychological state of mind such as stress contribute or cause diseases and cause body organs to fail?

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I’ve heard it multiple times that stress is the worst enemy. But how exactly is stress an enemy to body, like how does long term exposure to stress increase risks of getting diseases?

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There is a hormone your body produces when under stress called cortisol. That hormone is responsible regulating a wide range of bodily functions. It’s only meant to be present at high levels occasionally. If it’s present continuously for a long period of time, it can cause significant problems.

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