How does a wound know when to stop healing?

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A gash closes up and forms a scar but how does it know when to stop? How can, for example, a whole part of your liver be removed and it just grows back without filling your whole abdomen with liver tissue

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7 Answers

Anonymous 0 Comments

Without going into too much detail, our bodies have these things called negative and positive feedback loops. Essentially, when our body receives certain signals – these signals turn on certain responses in the body eg. eat too much sugar, insulin is made in order to lower our glucose levels. These signals keep coming until the body senses that it has lowered the glucose to an acceptable level and then the signals stop.

Once our body stops sending out these signals or our body reaches a certain point where these signals are no longer being produced, then the system stops and nothing else happens and that’s job done.

Edit: to make more clear:
Step 1: body needs more liver
Step 2: body says “we need more liver”
Step 3: part of body that makes liver says “okay boss, we’ll make more liver”
Step 4: body keeps making liver until boss says “okay we have enough liver”
Step 5: body stops saying “we need more liver”
Step 6: no more liver is made

Anonymous 0 Comments

Cells that grow back to heal wounds stop by “contact inhibition”. Basically, when they feel around and see that they’re surrounded by other cells, they stop dividing. But if you make a cut in the skin, they’ve suddenly lost half their neighbors and start growing in the direction where there’s space.

Anonymous 0 Comments

A wound stops healing when the body has successfully repaired the damaged tissue and restored normal function to the area. This process is regulated by a complex series of biological signals that help control the inflammatory response, cell growth, and tissue remodeling. Once the wound has been fully repaired, these signals gradually decrease, signaling the end of the healing process.

Anonymous 0 Comments

That’s amazing! So basically, our cells have a built-in social distancing technique. Wish humans had that.

Anonymous 0 Comments

Sometimes it doesn’t! Google proud flesh in horses. Seems it can happen in humans too. I’m only familiar with it from wound care in equines though.

Anonymous 0 Comments

Sometimes they don’t. You end up with bumps of what looks like fresh red scars, when really they may be years old.

Anonymous 0 Comments

Sometimes wounds stop healing before they are healed. Then they have to be derided, which kinda reminds the body hey this needs healed.