How does a the targeted cancer treatment kinase inhibitor Ayvakit work to treat Indolent Systemic Mastocytosis on a molecular level? What’s the process?
In: Chemistry
Avapritinib (brand name ayvakit) hits two kinases (KIT and PDGFRa) that are commonly mutated in some cancers, and then specifically the mutated forms they often end up in. Take out these cancer-driving proteins, cancer stops or at least becomes more vulnerable.
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