I’m going to ELI5 in a slightly more epistemological direction but it may help guide a lot of the questions from OP here. A carcinogen is something that, by definition, causes cancer. We don’t have the “mechanisms” for a ton of carcinogens. We just know that they’re probably things that cause cancer.
I remember someone from a drug company came in and talked to the chemistry students and it blew my mind when he told us that a similar thing was true for a lot of drugs. All we care about is “are they safe?” and “do they work?” When you think about it, knowing HOW they work would be nice, but I wouldn’t want to wait for that before giving it to people as long as I knew it was safe and it worked.
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