A lot of that dust will have been airbourne at the time the room was closed off, or will come from fabrics, wallpaper (and ceiling paper), and anything carried in there on draughts.
Since the room is closed and relatively still there’ll be a tendency for any air that gets in and is carrying dust to drop it, whilst any dust that does get disturbed only stirs around at relatively low levels in the room before settling again, whilst the air can leave higher up without disturbing any deposited dust.
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