How does microchimerism work if cells are constantly regenerating?

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Microchimerism is a phenomenon where women have small numbers cells which they inhereted from their fetus during pregnacy. the mother and the fetus swap trace amounts of cells during pregnancy, and since males have a y-chromosome it is easier to detect in women than if it were a female fetus.

The thing is that women who undergo microchimerism have been found to have these cell for a long time. How does this work given that cells replace themselves on a constant basis? Are these cells simply regenerating like any other cells?

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Anonymous 0 Comments

Yes, they do regenerate.

The way cell regeneration works is not that new cells are brought to the organ to replace the old ones: the old ones simply make a copy of everything inside them, then they divide and each new cell takes one exemplar of each.

That way the new cell is an exact copy of the old one, except for some random mutations (which here are errors in the duplication of DNA/RNA).

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