Hormones can cause cravings (making it harder to control intake), mismatched hunger/satiation signals (causing your body to lie about how hungry you are), and lower energy availability (making physical activity feel harder).
So just like a person with any issue CAN overcome that issue, hormonally fat people are capable of dealing with it by lowering intake and increasing activity, but it’s harder for them, and that amount of mental energy expenditure to be constantly managing diet and activity levels will probably preclude them from managing other things because there’s only so much mental energy to go around.
There are also a couple conditions which mess up storage and unpacking signals (also hormonal). The first makes your cells just turn sugar into fat too fast – basically it just makes it so eating food makes fat BEFORE it gives you energy for the day, so you always feel hungry and tired because you don’t have enough food in your system while constantly getting fatter. The second doesn’t let the fat turn back into sugar like it’s supposed to – thus you have to literally starve yourself to get the fat off because your system won’t consume it, it will literally start breaking down muscle tissue before it starts using fat stores. Obviously both of these conditions can lead to some excessive obesity and require medical management.
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