The human body does not monitor CO2 directly. It measures pH, which CO2 affects. It doesn’t monitor oxygen levels at all, which is why nitrogen gas is so dangerous: as long as you are breathing out CO2, you’ll feel fine – even if you aren’t getting any oxygen. There are many stories of people walking into a room filled with nitrogen and working happily for 4 minutes until they pass out and die.
Burrowing animals like rabbits and rats do actually monitor oxygen directly.
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