One of the most common causes is due to so called toxins (proteins) made by a bacteria called staphylococcus aureus, that lives on healthy peoples skin. These bacteria may grow rapidly on food at room temperature. When ingested these toxins can cause nausea, vomiting and diarrhea for which there seem to be several mechanisms relating to the immune system.
[in depth reading](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153270/)
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