There are quite a few “interesting” things we simply do not know about botulinum. The molecule is absolutely massive and should be to big to simply enter our bloodstream from the gi tract but yet it can.
It has been quite some years since i did a uni paper on botulinum and at the time there was very little research being done on the subject and i would guess there is little interest in knowing the finer details about how botox/botulinum moves through barriers that it should not because of its massive size
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