Say, a loved one has passed away, which results in depression…does the chemical imbalance come after the fact, what triggers the imbalance, and why is it blamed for the depression, and not the passing away of the loved one?
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The idea that depression is due to a chemical imbalance is just a hypothesis. It was made popular since it explained why SSRIs worked, but we now know that to be wrong.
The latest view is that depression isn’t due to serotonin imbalance.
>The main areas of serotonin research provide no consistent evidence of there being an association between serotonin and depression, and no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations.
>From <https://www.nature.com/articles/s41380-022-01661-0>
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