How is the half-life of a medicine designed to have a short half-life or a longer half-life?
For example, CONCERTA’s half-life is 3.5 hours, and another med, for instance, Trintellix – Vortioxetine, has a longer half-life of 66 hours.
In: Chemistry
Typically the half life is actually the opposite. It’s not designed to be a certain length of time.
That just happens to be how fast your liver or kidneys or other organs can process and break down that medication. The half life time wasn’t designed in a laboratory, it was discovered when they were testing different dosages of the medication in different people during the trials.
Now, they can do some thing to make medication “last longer” In The body, the most common being “delayed release” medications where they design the pill or capsule to take longer to dissolve in the stomach than a normal pill, meaning if you’re taking a 100 mg pill, instead of all 100 mg entering your blood at the same time, it gradually enters the blood over a longer period of time.
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