How the neuromuscular blocking medication ‘nimbex’ is broken down through Hofmann elimination?


Can someone simplify the process of Hofmann elimination please? I was just in a class where we discussed the pros and cons of different paralytic agents and this became a topic of interest. Appreciate any help!

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Nimbex is a neuromuscular blocking medication used to relax muscles during surgery. It works by binding to receptors in the brain that control muscle movement. Nimbex is broken down through Hofmann elimination, a process in which the medication is metabolized by the liver and converted into a less active form. This process occurs over a period of days, and the medication is eventually eliminated from the body through the kidneys.