Think of a radioactive atom like a tiny grenade that will sometimes shoot off a piece of shrapnel. If that shrapnel hits another grenade, it will knock off another piece of shrapnel, and now there are two pieces of shrapnel flying around, but most of the time it hits something that won’t break off another piece. This happens naturally underground in ore deposits, and emits a small amount of energy.
If you surround a chunk of radioactive material in something that will reflect that shrapnel, the chances of it hitting another grenade are increased. This will start a chain reaction that will gradually release more and more shrapnel flying around. This is what happened in the demon core.
If you surround the radioactive material in a normal explosive like C4 and detonate it simultaneously, it shoves all those grenades together into a super compressed ball where each shrapnel has a much higher chance of hitting another grenade. This produces an explosive release of energy seen in atomic bombs.
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