I heard of the case of Adam Rainer, where his apparent condition called “acromegaly” caused him to grow uncontrollably beyond adolescence. He was both a dwarf at 19 and a giant at 33. How is this possible if growth plates predetermine height?

Question

I’ve been wondering this for a pretty long time

In: Biology

Answer 1

Acromegaly is endocrin disease which causes by abnormal STH release after puberity. STH is simply growth hormon if it releases too much in puberity you become giant, other way you become dwarf, but in acromegaly it is releasing much after puberity.

End of the puberity your bones stops growing but the handa and feet. In that after puberity STH abnormality causes big hands and feet.

And about that thing if his STH released minimum before 19 his that means his bones too short but they have space to get bigger. If after 19 his STH levels increase bones can grow till there is no space. It is rare but he is suffering from 3 dissease which completes each other.