I’ve always heard that a singular dot of fentanyl can kill you. Yet we use it medically, for pain relief. And many people are addicted to it but stay alive while using. Is there like a different method of using it? How do people use it and not die?
In: Chemistry
Street fentanyl is on average only 14% pure in the USA according to DEA and around the same in Canada according to our many free drug testing places and databases, but anywhere from 8-20% usually.
The 2mg dosage you see in media is the (suspected) “LD50”, the lethal intravenous dose 50% of adults will die at. so its misleading in general because the media always says “2mg will kill anyone”.
So that 2mg figure you’re used to seeing is more like 20mg on the street, and that’s for IV which is the most bioavailable (efficient) route of administration (ROA).
This makes it easier for street users to not OD especially considering many are smoking it which is much less efficient RoA, and since it’s not even close to pure anyways. Once you take tolerance into account, usage can quickly double, triple, quadruple. This can make it more dangerous despite seeming like itd be safer – because of the discrepancies of potency between batches and the chance of hotspots and other cutting agents or research chemicals like etonitazene or fentalogues.
Most batches are color coded, so users can have somewhat of an idea that the green fent X is selling is maybe the same as the green Y is selling, while if they find a red batch from Z maybe they start at a lower dose and titrate up to ensure it isnt more potent than their last and causes an OD.
As for medical situations, its Volumetric Dosage. 100mg can be put into 100ml then each 0.1ml is 100ug for example. 1mg per ml concentration. People are also given patches which are like a controlled release idea.
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