If a fully immunodeficient person catches a cold, what will happen?

Question

There will be no body reaction like fever, aches, … So what will the person feel?

And in the end, will they die? What exactly will kill them?

In: 4

Answer 1

There’s really no such thing as no immune system, because the system is so complex and involving many, many parts of the body.
During chemo, my daughter got a cold and ear infection. Now, she has about 8000 white blood cells, and about 5000 neutrophils (neutrophils are the first line WBC). During chemo, she had about 100 WBC and 0 Neutrophils.
She got a fever, ear ache, cough, etc. The parts of the immune system that cause fever aren’t dependent on blood counts. The part that creates more mucus and a cough reflex aren’t dependent on blood counts. Through antibiotics, she fought the infection and recovered in about 2 weeks without ever having a significant amount of white blood cells.