You can notice something is genetic long before you can identify _what_ gene, geneS, or specific combination of genes (that individually do nothing significant), or *epigenetic* modifications (distinct from genes), or *combination* of genetics and epigenetics leads to conditions. Add to that, you can’t just compare two individuals, one with and one without, because there will also be *thousands* of other differences to mix in– you would be aiming to identify the cause behind *one* of these differences, independently, *somehow.*
Biology is fun, but it’s a very messy science and it’s often difficult trying to explain things definitively.
Noticing ADHD/autistic/other-condition parents more frequently have kids with a similar condition though, or related observations? Easy.
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