A lot of rocks are also chemically inert, but if you eat sand or breathe rock dust you’re going to have a problem. A chemically inert object in your body can hurt you if it’s solid and there isn’t supposed to be a solid object where it is.
Also the estrogen receptor has less discerning taste than most receptor proteins, so it doesn’t take much for a chemical to look like estrogen to your body, and some plastic additives fit the bill.
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