If both liver and kidneys are cleaning the blood, what’s the difference between them?

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If both liver and kidneys are cleaning the blood, what’s the difference between them?

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Kidney cells have selective pumps in their membranes allowing them to transport water soluble wastes from the blood into the urine. However, they are not efficient in removing lipid (fat) soluble wastes because the fats can diffuse into the urine and from the urine back into the blood.

The liver is designed to rid the body of fat-soluble wastes. These substances are excreted into the bile and eventually move into the intestines and from there to the toilet via the feces. The liver metabolizes other lipid soluble substances making them water soluble so they can be eliminated by the kidneys.

To completely “clean” the blood you need both organs working simultaneously.

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