If caffeine blocks the receptors for Adenison, which is responsible for feeling tired/exhausted, why does caffeine help me feel awake in the morning?

Question

After waking up my adenosine level should be very low and l slowly build up upon the day. So why does my morning coffee make me feel awake if there is no adenison to block?

In: 25

Answer 1

Over time, your neurons counteract the effects of caffeine exposure by producing more adenosine receptors. With more receptors, your neurons become more sensitive to low levels of adenosine. This leads you to need more caffeine to feel its effects, and some caffeine to feel “normal.”

[source](https://pubmed.ncbi.nlm.nih.gov/1888264/)

Answer 2

Over time, your neurons counteract the effects of caffeine exposure by producing more adenosine receptors. With more receptors, your neurons become more sensitive to low levels of adenosine. This leads you to need more caffeine to feel its effects, and some caffeine to feel “normal.”

[source](https://pubmed.ncbi.nlm.nih.gov/1888264/)