https://www.clinicaltherapeutics.com/article/S0149-2918(14)00457-3/fulltext
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The reason that colchicine isn’t currently prescribed for cancer is that colchicine will kill you before the cancer does.
It’s toxic at levels that are very close to the levels where it actually starts having positive effects – the cool kids would say it has a narrow theraputic window – and worse, there’s a very narrow range between where you start having symptoms of colchicine toxicity and where you stop because, well, you died.
If you were to take it to maintain a certain level in your system to have a constant effect on the cancer, you’d have to be incredibly precise with your dosages and your timing so you didn’t end up with either too little in your system leading to no effect on the cancer (bad) or too much in your system and you died from it (also bad).
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