I’m no expert (at biology, you better believe i’m one hell of a sedentariologist)
But it has more to do with cardiovascular health than musculature (also like every other part of the body is affected of course) being sedentary means you aren’t getting cardiovascular exercise, which as running and wandering organisms is *very* important to the normal fuctions of a homosapien. Poor cardiovascular health means your body is less efficient at spreading oxygen and other nutrients to your cells. Poor nutrition amd oxygenation of cells means they work harder and are more prone to errors or failure. Poor cardiovascular health is the #1 killer in the US, and creates more problems than I could list here.
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