if procreating with close relatives causes dangerous mutations and increased risks of disease, how did isolated groups of humans deal with it?

Question

if procreating with close relatives causes dangerous mutations and increased risks of disease, how did isolated groups of humans deal with it?

In: 562

Answer 1

You may find this article from a couple days ago interesting!

[Medieval Teeth From Ancient Ashkenazi Jews Indicate ‘Genetic Bottleneck’ Variation 600 Years Ago](https://www.sciencetimes.com/articles/41165/20221202/medieval-teeth-ancient-ashkenazi-jews-indicate-genetic-bottleneck-variation-600.htm)