if procreating with close relatives causes dangerous mutations and increased risks of disease, how did isolated groups of humans deal with it?

Question

if procreating with close relatives causes dangerous mutations and increased risks of disease, how did isolated groups of humans deal with it?

In: 562

Answer 1

[Oliver Sacks](https://www.oliversacks.com/oliver-sacks-books/the-island-of-the-colorblind/) wrote this book called The Island of the Colorblind that mostly talks about how the Micronesian island Pingelap deals with a large number of their residents being colorblind. While that is interesting enough to warrant a read, the whole thing starts when a few hundred years ago a tsunami (I think… it’s been 20 years since I read it) wiped out all but a few people, and what happened afterwards.