if Topiramate is anti-epileptic then why does it work for migraine ?

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[disclaimer] not sure how to label the tag, but this falls under medication!

Topiramate is a well-known medication prescribed for epilepsy but for it has also be used as off-label meds to help with migraine.

I don’t think I can ask any of my HCW this question, bcs I don’t want to be seen difficult. And from my google search, there seems to be lack of satisfying result (?) or explanation (?)

So yes, genuine curiousity. If Topiramate is anti-epileptic then why does it work for migraine ?

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3 Answers

Anonymous 0 Comments

Topiramate is a carbonic anhydrase inhibitor. That seems to have an effect on some migraines. I’m not actually sure of the direct mechanism.

Note, it also has a side effect of an appetite suppressant and also a mild antidepressant. Drugs have side effects. The side effects aren’t always negative.

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