if Topiramate is anti-epileptic then why does it work for migraine ?

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[disclaimer] not sure how to label the tag, but this falls under medication!

Topiramate is a well-known medication prescribed for epilepsy but for it has also be used as off-label meds to help with migraine.

I don’t think I can ask any of my HCW this question, bcs I don’t want to be seen difficult. And from my google search, there seems to be lack of satisfying result (?) or explanation (?)

So yes, genuine curiousity. If Topiramate is anti-epileptic then why does it work for migraine ?

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3 Answers

Anonymous 0 Comments

There are multiple reasons for why this may or could be. There are plenty of medications that are for disease A but treat disease B as well.

As for a specific answer? That’s outside the scope of an ELI5 as likely you’d need a detailed understanding of the chemical makeup of the drug, protein receptors in the body, and very complex chemical interactions that would allow for it to happen.

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