I can tell you that N-1-2-3-4 is not preferable. As a kid I had a Bridgestone 175cc dirt bike with N-1-2-3-4 gear pattern however, if you upshift from 4 the next gear would begin at N again then 1-2-3-4. When you forget this downshifting and find 4th gear when 1st was needed was nowhere near as terrifying as shifting from 4th into 1st at speed.
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