Answer to first question is overwhelmingly yes.
In very broad terms, fision and fusion are quite opposite of each other.
The actual processes that make fusion happen vs what makes fission happen are quite different. Fission is a process that can be hard to stop once it starts going, while fusion is a process that is hard to keep going and hard tobprevent it from stopping. In fission reactor, a huuuge ammount of material must be present at the core to function, while every viable design for fusion reactor has very tiny ammount of fusionalbe material in reactor. Fusion bomb only works because of very large ammount of fusionalbe material avaliable for reaction and it requires a fission bomb as the trigger.
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