They may be experiencing horrible effects from inbreeding as we speak. I think it is probably important to point out that they dont seem to have retained boat technology (extremely strange for island dwellers). It is also speculated that they have lost the capacity to make fire (fire is considered a human universal).
I mean, no one can say for sure but if both of those things are true I think it is safe to guess that inbreeding has wreaked havoc on those poor people.
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