I’ve seen cross-sectional slices of brains confirmed to have CTE (Chronic Traumatic Encephalopathy) and these slices all seem to differ greatly from a normal looking brain. Currently, why can’t a CTE diagnosis be confirmed with medical imaging, but only through autopsy?

Question

I’ve seen cross-sectional slices of brains confirmed to have CTE (Chronic Traumatic Encephalopathy) and these slices all seem to differ greatly from a normal looking brain. Currently, why can’t a CTE diagnosis be confirmed with medical imaging, but only through autopsy?

In: 285

Answer 1

Lots of things make your brain look weird at large scale, in largely similar ways. To determine which particular thing made any particular brain look weird, you need microscopic level detail, only available at autopsy.