Once a opioid addict has stopped using, are the dopamine and serotonin receptors completely fried, or do they heal themselves and begin to release the chemical without the intoxicant

Question

Once a opioid addict has stopped using, are the dopamine and serotonin receptors completely fried, or do they heal themselves and begin to release the chemical without the intoxicant

In: Other

Answer 1

A follow up question would be – when they come back, do they come back all the way or is there permanent downregulation?