EDIT: For specificity, I’m on buspirone 7.5mg twice daily, but often miss a dose (unintentionally of course, life happens). When this happens, I’ll usually double up, even knowing I’m not “supposed” to, in order to stay on schedule.
In: 2
Yes there is a difference, because the half-life decay (actually your liver processing and getting rid of the medication) is [not linear](https://saylordotorg.github.io/text_general-chemistry-principles-patterns-and-applications-v1.0/section_18/261586c1c0844e5efa716d77033046ea.jpg). You’re imagining a linear decay but it’s not.
So not only are you spiking too high and too low when you skip and double-up, but it’s possible that your spikes can overload your liver. Fortunately for you, buspirone doesn’t seem to have a high [hepatotoxicity](https://www.ncbi.nlm.nih.gov/books/NBK547966/).
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