EDIT: For specificity, I’m on buspirone 7.5mg twice daily, but often miss a dose (unintentionally of course, life happens). When this happens, I’ll usually double up, even knowing I’m not “supposed” to, in order to stay on schedule.
In: 2
If you mean one dose versus 2 half doses then yes, you you will spend more time overall in the therapeutic dose range with 2 half doses. With one bigger dose you might spike out of the therapeutic range initially into the overdose range then taper down into the therapeutic range and eventually into the underdose range before your next dose. The goal of extended or controlled release drugs is to keep you in the therapeutic range longer. More frequent smaller doses are a less automatic way to accomplish the same thing.
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