Serotonin is the hormone what makes us happy, so why aren’t we just injecting it into our body/taking it as tablets to get out of misery on command?
In: Biology
That’s what antidepressants are, they basically stimulate the body to release more serotonin, enhance the effect of serotonin and maintain more serotonin in the brain.
So why when you take Antidepressants, you need to wait at least a month before feeling the effects of i t?, and why it only works for some people and not others (60 % 40 statistically) This would mean that serotonin doesn´t cause direct happiness, but in constant high amounts in the brain it seems to change some neurological processes that relieves depression. (that’s why it takes antidepressants a month to work).
Depression its related to inflammation and cognitive impairment, It is presumed that depression can literally lower your IQ, because parts of the brain that are chronically inflamed start to die off in the brain. it seems that high amounts of serotonin stimulate Neurogenesis and neuroplasticity, wich makes new neurological pathways that fix previous inflamed ones. this could be why antidepressants work for some, Their depression were related to some kind of inflammation and low neuroplasticity associated with low serotonin, which its just one case of depression.
In a few words: depression it’s not hormones, there are a lot of very complex process that are happening behind each case of depression, and they can have very differences causes. there is no direct cause, just possible causatives: Inflammation, Low Dopamine, Gaba/Glutamate dysregulation, Low Serotonin, Neurodegeneration, Autoinmune responses, external virus/bacterial infections,Vitamin deficiency, etc…
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